Stress-driven lymphatic dissemination: An unanticipated consequence of communication between the sympathetic nervous system and lymphatic vasculature

نویسندگان

  • Caroline P. Le
  • Erica K. Sloan
چکیده

Chronic stress drives cancer progression, but the routes of metastasis are unclear. We recently demonstrated that chronic stress activates a neural-inflammatory signaling axis to remodel lymphatic vasculature and increase lymph flow. This unanticipated crosstalk between stress and the lymphatic system provides pathways of tumor cell dissemination and accelerates metastasis.

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عنوان ژورنال:

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2016